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Much-loved entertainer Russ Abbot stars as an injured pet shop proprietor facing the loss of his home and business, and the F2s are given their first patient to treat alone - with alarming results - as the medical drama continues.

During a heated discussion with his landlord, pet shop worker Malcolm slips while holding a fish tank and suffers severe lacerations. Whilst Malcolm is in casualty the landlord is forced to reveal that he wants to build a car park on the site of the pet shop, and Malcolm and his wife Brenda face losing their home and livelihood. Yuki needs to use all his diplomacy skills when, at the end of his tether, Malcolm decides to take matters into his own hands.

F2s Yuki, May and Lenny are thrilled when Adam gives them their own patient to treat - Ruth's friend Amir, who has a history of heart problems. Ignoring advice from Jordan, the F2s follow their own course of treatment, with disastrous results. And things go from bad to worse when the patient then goes missing. The F2s hide their panic, but are individually distraught; have they really messed up this time?

Meanwhile, paramedic Polly receives some disturbing news about Alistair, which she responds to calmly. But what is affecting Polly's normally sunny disposition, and why is she behaving so strangely around certain patients?