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With the prime minister proposing an end to self-isolation requirements as early as the end of the month, we thought we would check in with all things pandemic-related this week.

We hear from mathematical biologist Dr Kit Yates from the University of Bath and UCL鈥檚 Professor Christina Pagel, who, like many scientists, are concerned about the consequences of relaxing protective measures. However, epidemiologist Professor Irene Petersen tells us why she feels it is the right time to loosen restrictions.

A new omicron sub-variant has been making headlines this week. Professor David Male takes us through what we know about omicron BA.2 so far.

And from possible endings to the pandemic鈥檚 origin story. Roland Pease spoke to Beijing-based journalist Jane Qiu who鈥檚 gained unprecedented access to the Wuhan scientist at the centre of lab leak theories.

Presented by Marnie Chesterton
Producer Samara Linton
Assistant Producer Emily Bird
Made in association with The Open University